Valmore Bermúdez
School of Medicine, Endocrine and Metabolic Diseases Research Center,
The University of Zulia, Maracaibo
Venezuela
Case Report
A Hyperglycemic, Obese and Fast-Weight Losing Adult: A Case Report on Latent Autoimmune Diabetes with Low Anti-Gad65 Titers
Author(s): Carmen Suárez, Carmen Chávez, Adriana David, Miguel Aguirre, Joselyn Rojas, Manuel Velasco and Valmore BermúdezCarmen Suárez, Carmen Chávez, Adriana David, Miguel Aguirre, Joselyn Rojas, Manuel Velasco and Valmore Bermúdez
Introduction: Latent Autoimmune Diabetes in Adults (LADA) is an autoimmune endocrine disorder, in which in spite of having positive anti-islet antibodies, the progression to full blown beta cell destruction and insulin insufficiency is slower. This scenario is often mistaken by other types of diabetes and due to this misdiagnosis the initial treatment is often mistaken.
Clinical case: Male subject, 26 years of age, obese at the moment of the first hyperglycemic crisis, with a previous diagnosis of Type 2 Diabetes Mellitus (T2DM) 3 years before arriving to our institution. He refers to have been on oral treatment for his disease with no metabolic control, finally succumbing to polyuria, polydypsia and an important weight loss of 30 kg in the course of 1 year. Family history shows first and second degree history of T2DM. Upon arrival, physical examination showed 140/85 mmHg, BMI.. View More»
