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Wenda Gao | OMICS International
ISSN: 2576-1420

Journal of Infectious Diseases and Medicine
Open Access

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Wenda Gao

Antagen Pharmaceuticals, Inc., 650 Albany St., STE 112, Boston, MA 02118

Identification of a Guinea Pig Fcγ Receptor that Exhibits Enhanced Binding to Afucosylated Human and Mouse IgG

Glyco-engineered recombinant antibodies are currently being developed as the next generation therapeutics to treat human diseases, including cancer, autoimmunity and infection. Antibodies lacking core fucosylation show great increase in affinity for FcγRIIIA, leading to an improved receptor-mediated effector function. While afucosyl human IgG1... Read More»

Changchuin Mao, Richard Near and Wenda Gao

Short Commentary: J Infect Dis Med, an open access journal

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article