Translational Medicine
Open Access

Wilson IB Onuigbo

Publications

• Research Article
  Does the Erythrocyte Associated Necrosis Factor Explain the Scarcity of Metastases in the Spleen?
  Author(s): Wilson IB OnuigboWilson IB Onuigbo
  
  The grand anatomical eminence of the spleen rests, among other things, on its manufacture of erythrocytes, the littoral cells allowing traffic of blood cells between cords and sinuses. Manifestly endowed is the heart that pumps these cells and cancer cells to the spleen. In this context, lung cancer is best poised to scatter its millions of members to any organ including the spleen. Clearly, lung cancer cells and erythrocytes must commingle in the spleen. Elsewhere, such commingling was shown to lead to obvious cancer necrosis. Therefore, an Intrinsic Factor was reasoned to be responsible for such necrosis within the thoracic duct. It was named personally as the “Erythrocyte Associated Necrosis Factor” (EANF). Now, in the Theoretical Sciences, a hypothesis is held to have “operational power” if a result validates it. Therefore, for confirmation, repeated valida.. View More»
  DOI: 10.4172/2161-1025.1000177

  Abstract PDF

Relevant Topics