Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Xiao-Ni Wang
China
Research Article
Observation Study of the Retina with the Alzheimers Disease or Amnestic Mild Cognitive Impairment Patients
Author(s): Yue Wu, Xiao-Ni Wang, Ningli Wang, Ying Han and Yan LuYue Wu, Xiao-Ni Wang, Ningli Wang, Ying Han and Yan Lu
Objective: We investigated the regularity changes of the retinal nerve fiber layer (RNFL) and macular ganglion cell complex (mGCC) of the Alzheimer’s disease (AD) and amnestic Mild Cognitive Impairment (aMCI) patients. Methods: 24 AD patients, 22 aMCI patients and 30 health controls whose age were above 60 years old were recruited in the study. The RNFL thickness and the mGCC average thickness were measured by Fourier-domain optical coherence tomography (FD-OCT). Results: Compared with the controls, we found statistically significant lower of the intraocular pressure (IOP) in the AD and aMCI patients. When compared with the AD patients and controls, aMCI patients showed a significant decrease in RNFL thickness in ST (Superior Temporal), TU (Temporal Upper) and temporal (TU+TL) quadrants. The average thickness of the mGCC was significantly thinner in the aMCI patients than in the.. View More»
DOI:
10.4172/2155-9570.1000545