Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
+44 1478 350008
ISSN: 2161-1017
+44 1478 350008
Zhao-Qian Liu
Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics,
Changsha, Hunan 410078
IR Iran
Review Article
Pharmacogenetics of Oral Antidiabetic Drugs: Potential Clinical Application
Author(s): Ji-Ye Yin, Yu Guo, Qiong Huang, Hong Sun, Hong-Hao Zhou and Zhao-Qian LiuJi-Ye Yin, Yu Guo, Qiong Huang, Hong Sun, Hong-Hao Zhou and Zhao-Qian Liu
Oral antidiabetic drugs (OADs) are widely used to treat type 2 diabetes mellitus (T2DM). However, inherited difference is one of the major issues that affect OADs therapeutic efficacy. In the present paper, we performed a critical review on recent advances in genetic polymorphisms that influence OADs therapeutic efficacy and metabolism. Sulfonylureas (SUs), Meglitinides, Metformin and Thiazolidinediones (TZDs) will be discussed... View More»
DOI:
10.4172/2161-1017.S5-003