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Zuguang Ye | OMICS International
ISSN: 2470-6965

Malaria Control & Elimination
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Zuguang Ye


Antimalarial Activity of Various Bisbenzylisoquinoline and AporphineBenzylisoquinoline Alkaloids and their Structure-Activity Relationships against Chloroquine Sensitive and Resistant Plasmodium falciparum Malaria in vitro

The antimalarial activity of some bisbenzylisoquinoline (BBIQ) alkaloids were studied using in vitro culture of both chloroquine (CQ)-sensitive and chloroquine-resistant strains of Plasmodium falciparum. The combination of chloroquine and tetrandrine gave a 44 fold potentiation of malarial killing. Fangchinoline, hernandezine, pycnamine, berbamine ... Read More»

Zuguang Ye and Knox Van Dyke

Research Article: Malaria Contr Elimination

DOI: 10.4172/2470-6965.1000137

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article