Cooley’s anemia is caused by mutations in the beta chain of the hemoglobin molecule. There is one beta chain gene on each 11th chromosome, for a total of two. How these genes are altered determines the specific type of beta thalassemia in a child. This form of thalassemia is usually so severe that it requires regular blood transfusions. The symptoms of Cooley’s anemia generally appear before a child’s second birthday. The severe anemia related to this condition can be life-threatening.
Treatment for beta thalassemia may include Regular blood transfusions, Medications, Surgical removal of the spleen, Daily doses of folic acid supplements, No iron supplements and Bone marrow transplantation from a matched donor is the only cure currently available for Cooley’s anemia.
Cooley’s anemia effects approximately 1 in 272,000 or 0.00% or 1,000 people. In USA 38 from 10,348,276 people were affected from Cooley’s anemia.