Inflammatory Bowel Disease

Severe diarrhea, pain, fatigue and weight loss. IBD can be debilitating and sometimes leads to life-threatening complications.Doctors use one of two approaches to treatment: "step-up," which starts with milder drugs first, versus "top-down," which gives people stronger drugs earlier in the treatment process.Inflammatory bowel disease (IBD) involves chronic inflammation of all or part of your digestive tract. IBD primarily includes ulcerative colitis and Crohn's disease.

The incidence of UC in children over the same time period was 2.8 (95% CI 1.9–4.0) per 100,000 per person years.7 These rates are somewhat higher than those reported in other pediatric studies, although similar to those reported in modern studies from Canada,3,8,9 Norway,10 and Finland.11 In a recent systematic review of international trends in pediatric IBD incidence, over 60% of studies reported a rising incidence of CD and 20% reported a rising incidence of UC.

Crohn's disease is an IBD that cause inflammation of the lining of your digestive tract. In Crohn's disease, inflammation often spreads deep into affected tissues. The inflammation can involve different areas of the digestive tract the large intestine, small intestine or both.