It is a relatively rare, chronic inflammatory skin disease characterized by asymptomatic, flat-topped and skin-colored micropapules. Lichen nitidus mainly affects children and young adults. The skin is primarily affected in this condition. Mucous membranes and nails also may involve. Lichen planus can clinically mimic and can sometimes coexist with lichen nitidus. Lichen nitidus is a benign disease with no associated mortality or complications. Lesions are typically distributed on the penis, genital area, abdomen, and extremities. Various clinical forms of the disease such as confluent, vesicular, hemorrhagic, palmoplantar, follicular, perforating, linear are often defined. The generalized form of the disease is rare.
A case study in Belgium revealed that lichen nitidus (LN) was found to be associated with Crohn’s disease. Some histological features, namely circumscribed epithelioid infiltrates, suggest a relationship between both diseases.