Non-polio enterovirus infections cause symptoms and signs such as sneezing, mouth blisters, and fever. Symptoms and signs of EV-D68 infection include rash, cough, and breathing problems. Treatment focuses on supportive care, such as oxygen therapy, inhaled steroids, and ventilator support In an epidemiological survey of NPEV and HPeV types detected from stool and cerebrospinal fluid (CSF) samples from patients admitted to hospital in the period from 2007 through 2011, a total of 330 patients were found positive for a NPEV (n=229), HPeV (n=184), or both (n=31) by real-time RT-PCR in stool and/or CSF as described previously.
Non-polio enterovirus infection is very common, and it is likely that pregnant women may be exposed to someone with the illness. Like most adults, pregnant women who develop an infection with one of the non-polio enteroviruses will likely have no symptoms of the infection or have only mild symptoms.