alexa Hepatic Steatosis Markers in Diabetic Rats Trained at the Aerobic/ Anaerobic Transition

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Hepatic Steatosis Markers in Diabetic Rats Trained at the Aerobic/ Anaerobic Transition

Aims: To analyze the effects of exercise performed at the aerobic/anaerobic transition (Lan) on Non-Alcoholic Hepatic Steatosis (NAHS) markers in type 1 diabetic rats. Methods: Adult Wistar rats were separated into four groups: Sedentary Control (SC), Trained Control (TC), Sedentary Diabetic (SD) and Trained Diabetic (TD). The trained groups swam supporting workloads equivalent to the Lan for one hour/day, five days/week, for eight weeks. Body weight, serum albumin concentrations, glucose concentrations, Free Fatty Acid (FFA) concentrations, NAHS markers (Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) and total lipid concentrations in the liver were analyzed. Results: The diabetic groups showed higher serum glucose concentrations and more weight loss compared to the controls, although the TD group was less affected than the SD group. Training resulted in a decrease in serum glucose levels in the diabetic rats. The NAHS markers, total lipid concentrations in the liver and serum albumin concentrations did not differ between the groups. However, the diabetic animals had higher serum FFA levels than the controls.

 

de Moura LP, Gomes RJ, de Almeida Leme JAC, de Araújo MB, de Mello MAR (2013) Hepatic Steatosis Markers in Diabetic Rats Trained at the Aerobic/ Anaerobic Transition. J Liver 2:137. doi: 10.4172/2167-0889.1000137

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