alexa Von Willebrand Disease

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Von Willebrand Disease

Von Willebrand disease (VWD) is a common hereditary bleeding disorder, inherited either as an autosomally dominant or recessive trait. It is caused by a quantitative and/ or qualitative defect in the Von Willebrand Factor (VWF) which plays two critical roles in hemostasis i.e., platelet adhesion and aggregation to damaged endothelium, and also as a carrier for Factor VIII (FVIII) molecule which stabilizes FVIII in the circulation.

 

 

Citation: Mohanty D (2014) Von Willebrand Disease: An Update. J Blood Disorders Transf 5:238. doi: 10.4172/2155-9864.1000238

 
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