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Cognitive Behavioural Therapy (CBT) with care as usual by the General Practitioner (GP) found the first to be more effective. However, to make a fair comparison GP care should be optimised and protocolised according to current evidence based guidelines for depression. So far this has not been the case. We studied whether a protocolised 8 session CBT is more effective than optimised and protocolised GP car. Effect sizes comparable to the (statistical significant) results from meta-analyses, together with lower AD prescriptions, are both in favour of brief CBT which might make it a first choice treatment for patients with MDD in general practice.
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