alexa Human Immunodeficiency Virus-Infected Children

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Human Immunodeficiency Virus-Infected Children

HIV-infected children and adolescents remain susceptible to measles and mumps despite two doses of the MMR vaccine; we recommend that antibody titers to MMR be evaluated in HIV-infected children following vaccinations as a means of assessing the primary vaccine response, including subsequent monitoring as deemed clinically necessary. Passive immunoglubulin administration may also be considered for these high risk children when exposed to measles and mumps, regardless of their vaccination status. Further prospective and larger studies may need to be performed in HIV-infected children to determine if lower immunities in this group are due to primary vaccine failure or waning immunity.

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