alexa Classification of Antiretrovirals

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Classification of Antiretrovirals

Antiretroviral therapy (ART) refers to the use of pharmacologic agents that have specific inhibitory effects on HIV replication. The use of less than three active agents is not recommended for initiating treatment. These agents belong to six distinct classes of drugs: the Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs, NtRTIs), the Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), the Protease Inhibitors (PIs), the Fusion Inhibitors (FIs), the CCR5 co-receptor antagonists, and the Integrase Strand Transfer Inhibitors (INSTIs).

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