alexa Secondary Sarcomatous Transformation in Mature Cystic Teratoma: An Uncommon Cause of Acute Abdomen

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Secondary Sarcomatous Transformation in Mature Cystic Teratoma: An Uncommon Cause of Acute Abdomen

Malignant transformation in a mature cystic teratoma is rare and sarcomatous change is even rarer. We report a case of 57 year old post-menopausal woman who presented with tender abdominal mass and fever. She underwent Total Abdominal Hysterectomy with Bilateral Salpingo-oophorectomy. Left ovary showed a mature cystic teratoma with solid areas. Histopathology of these solid areas showed a high grade spindle cell sarcoma which exhibited Vimentin and SMA positivity on Immunohistochemistry and was thus diagnosed as leiomyosarcoma. In most instances malignant transformation cannot be diagnosed pre-operatively. Most of these tumors are considered resistant to radiation and systemic chemotherapy and carry a poor prognosis.

 

 

 

citation:

Shirazi N, Harsh M, Chaudhary DN, Mahajan D (2014) Secondary Sarcomatous Transformation in Mature Cystic Teratoma: An Uncommon Cause of Acute Abdomen. J Integr Oncol 3: 122.

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