The 5-year survival rate after elective open surgical repair of Abdominal Aortic Aneurysm (AAA) is about 70%. Thus, the mortality rate among patients who have undergone repair (30%) is about as high as that among patients with stage II gastric cancer or stage III rectal cancer . Possible reasons for the relatively high mortality after AAA repair include the advanced age of the patients and the presence at operation or afterward of various comorbid conditions, especially cardiovascular disease, cerebrovascular disease, and cancer . It is also possible that onset of a thoracic aortic disease event such as Thoracic Aortic Aneurysm (TAA) or aortic dissection, the causes of which are similar to those of AAA, may affect the prognosis of a patient in whom AAA repair was performed years earlier . However, the incidence of TAA and aortic dissection after AAA repair, the possible effect of these events on long-term post-repair survival, and factors associated with onset of thoracic aortic events after repair have not been well studied. We therefore assessed the effects on survival after AAA repair of onset of TAA or aortic dissection. We also investigated risk factors for those events by comparing demographic, comorbid, operative, and laboratory variables in patients in whom an event occurred during a follow-up period of up to 25 years with the same variables in patients who did not have an event.
Matsumoto T, Kawakubo E, Matsuda D, Takano T, Okadome J et al. (2014) Late Onset of Thoracic Aortic Disease Events after Abdominal Aortic Aneurysm Repair: Effect on Survival and Possible Associated Factors. Angiol 2:126.