alexa Demyelinating diseases

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Demyelinating diseases

Nerves are protected in the body by a coating called myelin. When myelin is worn away or damaged, nerves don’t work as well. They can deteriorate, causing problems inside the brain and throughout the body. Damage to the myelin sheath around nerves is called demyelination. The term demyelination describes a loss of myelin with relative preservation of axons. This results from diseases that damage myelin sheaths or the cells that form them. These diseases should be distinguished from those in which there is a failure to form myelin normally (sometimes described as demyelination). Although axons that have been demyelinated tend to atrophy and may eventually degenerate, Demyelinating diseases exclude those in which axonal degeneration occurs first and degradation of myelin is secondary

 
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