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The safety of patients and the safe use of medicines are high priorities in the modern world. The first practical international co-operation in drug monitoring started in 1968. The ideas came up as a consequence of the so-called thalidomide tragedy. In the 1960s it was discovered limb deformities in babies may occur if thalidomide, ingested by mothers during pregnancy. This incident became the modern starting point of a science focusing on patient problems caused by the use of medicines. This science, and activities associated with it, is now most commonly called pharmacovigilance.
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