alexa Determination of Drugs and Metabolites in Raw Wastewater Using Liquid Chromatography-Mass Spectrometry

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Determination of Drugs and Metabolites in Raw Wastewater Using Liquid Chromatography-Mass Spectrometry

A previous study in Lubbock, TX detected the cocaine metabolite benzoylecgonine in wastewater entering the municipal wastewater treatment plant. This work was conducted using chemical derivatization followed by gas chromatography-mass spectrometry (GC-MS) determination. This is a report using liquid chromatography-mass spectrometry (LC-MS) for determination of drug metabolites isolated from wastewater in Lubbock, TX by solid phase extraction (SPE). Using the LC-MS method, chemical derivatization is eliminated and multiple analytes can be determined in a single run. The results obtained showed that several compounds from different drug classes were detected. Compounds observed included cocaine, heroin, tetrahydrocannabinol, amphetamine, and benzodiazepine derivatives.

Citation: Klein DM, Pandey G, Blackwell B, Sperry K (2015) Determination of Drugs and Metabolites in Raw Wastewater Using Liquid Chromatography-Mass Spectrometry. J Forensic Res 6:268. doi: 10.4172/2157-7145.1000268

 
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