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Celiac Disease (CD) or gluten sensitive enteropathy is an autoimmune disorder characterised by variable presentations which respond to exclusion of wheat and other gluten containing products. While exclusion of gluten is the corner stone in the management of this entity, newer therapeutic approaches are now being investigated. These include use of elemental diets, oral prolyl-endopeptidases, IL-15 blockage, transamidation of wheat and use of probiotics. With newer therapeutic approaches it might be possible in future for patients with CD to continue to take gluten while remaining symptom free.