The medicine in present era is much advanced and evidence based. Ayurveda offers a unique opportunity to evolve a science of healthy, harmonious and long life. Its holistic approach to health and disease, involving body, mind and spirit, can provide a broader framework to understand research data emerging from reductionist biomedical Sciences. A fresh perspective on the scope of scientific research on the basic concepts of Ayurveda came from a decadal vision document highlighting the importance of Ayurvedic biology. In ancient system of healing all Ayurvedic drug formulation have an inbuilt safety profile but it is necessary to produce the evidence based documents for the safety and efficacy of Ayurvedic drugs. Therapeutic efficacy of any drug or formulation mainly depends on quality control of pharmaceutical processes.