Patients with end-stage renal disease who receive peritoneal dialysis have a chance of malnutrition including hypoalbuminemia which occurs mainly due to the leakage of albumin through peritoneal membrane. A study included 36 patients on continuous ambulatory peritoneal dialysis (CAPD) were taken in which one group (20), have the exchanges replaced with a daily dose of 2000ml of peritoneal dialysis solution with 1.1% amino acids (AAs). The other group (16) was given oral supplementation of keto/amino acids.
The baseline albumin levels in the IP AA group were lower than the Oral AA group (p=0.008). Although treatment with AAs supplements administered either intraperitoneally or orally, can be considered a good nutritional support, it should be borne in mind that the important point is to increase the amount of dietary protein intake in individual patients.