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It has been more than four decades since cells were first used successfully in bone marrow and organ transplants, but the strategies envisioned today are more complex, involving manipulating cells based on new knowledge of how genes program their development and inner workings.
Cells of the immune system are among those that naturally carry out critical functions, but researchers are working on manipulating them to create better-targeted and more effective therapies. For instance, immune responses directed against cancer often are weak, so scientists are engineering and growing populations of immune cells that target specific molecules found on cancer cells. Already, remarkable recoveries from deadly leukemia have been credited to these new experimental treatments.
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