alexa EGF+61 A>G Polymorphisms and Lung Cancer Risk: Future Directions

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EGF+61 A>G Polymorphisms and Lung Cancer Risk: Future Directions

Lung cancer accounts more than 1.5 million patients worldwide. It is the leading cancer cause among male, accounting 23% of total cancer cases and 14% of cancer deaths. Non-small-cell lung cancer (NSCLC) comprises approximately 80-85% of lung cancer; and small-cell lung cancer, 15-20%. Adenocarcinoma and squamous cell carcinoma are the most common histological types among NSCLC. To date, many risk factors are associated with lung cancer risk, such as cigar smoking, age, race, gender, randon exposure, and wood smoke exposure, environmental and occupational exposure. Genetic influence is a topic that is not completely understandable, but increasing evidence suggests that such factors play important role. Recently, a wide association genome study found that a single nucleotide polymorphism (SNP) at chromosome 13q31.3 was associated with an increased risk of non-small cell lung cancer.

EGF+61 A>G Polymorphisms and Lung Cancer Risk: Future Directions

 
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