The CD163 glycoprotein is a member of the scavenger receptor cysteine-rich superfamily acting as an inflammatory modulator inducing anti-inflammatory pathways. Previous findings from our group identified this gene as being differentially expressed in visceral adipose tissue (VAT) of severely obese men with vs. without the metabolic syndrome. The current study aimed to test the association between CD163 gene polymorphisms and obesity-related metabolic complications.
Citation: Guénard F, Cormier M, Tchernof A, Deshaies Y, Biron S, et al. (2014) Common Sequence Variants in CD163 Gene are Associated with Plasma Triglyceride and Total Cholesterol Levels in Severely Obese Individuals. Endocrinol Metab Synd 3:146. doi: 10.4172/2161-1017.1000146