alexa Pathogenesis of PTSD

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Pathogenesis of PTSD

The public health significance of PTSD, relatively little is known about the etiology or pathophysiology of this disorder, and pharmacotherapy development to date has been largely opportunistic instead of mechanism based. One promising target for modulation is Tropomyosin Receptor Kinase B (TrkB), the receptor for Brain-Derived Neurotrophic Factor (BDNF), a signaling pathway important for neuronal plasticity, survival, and growth.

Citation: Green CR, Corsi-Travali S, Neumeister A (2013) The Role of BDNFTrkB Signaling in the Pathogenesis of PTSD. J Depress Anxiety S4:006

 
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