Endothelial cell in comparison to many other cell types, were thought to be less active, less complex, and less interesting. Research in this area has expanded dramatically since then, revealing the endothelial lining as an active participant in a wide variety of pathophysiological processes, including inflammation and immunity.
Citation: Parmar N, Hutchison J, Vomiero G, Kumar A, Abdelhaleem M, et al. (2015) Altered Adhesion Molecule Expression of Leukocytes of SCD Patients in Crisis and Steady State. J Blood Disorders Transf 6:262. doi: 10.4172/2155-9864.1000262