Nowadays, the increasing use of pharmaceutical compounds in human and in animals is becoming a new environmental problem and, because of that, the interest in having information about their presence in the environment and their possible adverse effects on human and on ecological systems is considerably increasing. This class of compounds includes substances that are widely used in agriculture, medicine and biotechnology, such as antibiotics, drugs and hormones. The occurrence and fate of PhACs compounds has become a major issue of concern and research for the 21st century. The investigations carried out in developed countries such as USA, Canada, Japan, Korea, Australia and many countries in Europe, more than 80 compounds have been detected in the aquatic environment. It is estimated that worldwide consumption of active compounds amounts to some 100 000 tons or more per annum.