alexa Stereochemistrical Determination of Dexlansoprazole by Optical Rotation, ECD and 13C-NMR

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Stereochemistrical Determination of Dexlansoprazole by Optical Rotation, ECD and 13C-NMR

Dexlansoprazole is an outstanding proton pump inhibitors, which is a chiral sulfoxide. We firstly report determination of the absolute configuration (AC) of dexlansoprazole by the combination of experimental and calculated optical rotation (OR), electronic circular dichroism (ECD) and 13C-NMR. The high agreement between theoretical and experimental data illustrates that this method would be used to determine the absolute configuration of chiral sulfoxide.

Citation: Zhou Z, Li L, Yan N, Du L, Sun C, et al. (2015) Stereochemistrical Determination of Dexlansoprazole by Optical Rotation, ECD and 13C-NMR. Med chem 5:235-240. doi: 10.4172/2161-0444.1000270

 
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger