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Heart transplantation in infants and children is now accepted therapy. According to the registry of the International Society for Heart and Lung Transplantation, approximately 350-500 pediatric heart transplantation procedures are performed worldwide each year, representing about 12% of the total number of heart transplants performed. In 2012, 512 heart transplants were performed in children worldwide. The proportion of pediatric transplant patients by recipient age has remained relatively stable for over last decade