alexa Assessment of Redox Imbalance in Idiopathic Fetal Growth Restricted Pregnancies

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Assessment of Redox Imbalance in Idiopathic Fetal Growth Restricted Pregnancies

Fetal growth restriction (FGR) is the second leading contributor to perinatal mortality after prematurity [1]. The incidence is between 3-10% in developed countries, which increases to approximately 20% in developing countries [2]. FGR neonates have an increased perinatal and infant mortality and are more prone to cardiovascular disease, obesity and diabetes in adulthood [3]. There are multiple maternal, fetal and placental disorders that affect fetal growth. The known causes are poor maternal nutrition, hypertensive disorders complicating pregnancy, maternal medical disorders (multiple pregnancy, congenital fetal malformations), and lifestyle influences [4]. However, in vast majority of cases, the cause still remains unknown. Recent literature suggests the role of increased redox imbalance as an ultimate step in etiology of these cases of idiopathic origin [5,6].

 
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