Malaria remains a major public health problem globally. It is estimated that each year there are about 350–500 million clinical cases of malaria, which result in more than 1 million deaths. About 80% of these deaths occur in children under five years old that live in areas of intense malaria transmission, notably in sub-Saharan Africa. The most severe form of malaria otherwise called cerebral malaria is caused by resistant Plasmodium falciparium infections and constitutes about 95% of all malaria cases reported to heath care facilities in Ghana. The treatment requires prompt, safe, and effective intravenous anti-malarial drugs.