Pancreas divisum (PD) is one of the embryologic anomalies of the pancreas, in which the dorsal and the ventral pancreatic ducts fail to merge together. In this case the ventral pancreatic duct appears small and most of the pancreatic juice is drained through the minor papilla into the duodenum. Intraductal papillary mucinous neoplasia (IPMN) represents a heterogeneous group of pancreatic neoplasms. This kind of tumor may have its development in PD. Recently, owing to the progress in imaging and endoscopic ultrasound (EUS) techniques about the evaluation of the pancreas; the IPMN has been more and more identified and referred by the literature.