alexa A Comparative study of quality control tests for eye preparations as per IP, BP and USP

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A Comparative study of quality control tests for eye preparations as per IP, BP and USP

Present study deals with a brief review of the quality control tests for the eye preparations as per the different pharmacopoeias. The quality control tests for eye preparations are different in the different pharmacopoeias like IP, BP, and USP. Eye preparations are sterile liquid, semi-solid or solid preparations intended for administration upon the eyeball and/or to the conjunctiva, or for insertion in the conjunctival sac.It is necessary to know the quality requirements of the different pharmacopoeias for the eye preparations as it is required and important to guarantee the quality product and their supply in different markets of the world. The main aim of the study is to compare the quality control tests for eye preparations as per the IP, BP and USP. The formulations which are taken in to consideration are eye drops, eye ointments, powders for eye drops and eye lotions, semi-solid eye preparations, ophthalmic inserts and eye lotions (or) eye solutions. The types of tests/parameters, procedures and the pharmacopoeial limits/specifications for eye preparations were compared.The quality control tests for different eye preparations are more elaborately given in IP and BP in comparison to USP. The available tests and limits supplement each other and one pharmacopoeia gives more details on a specific test than the other. For eg: Powders for eye drops and eyelotions, semi-solid eye preparations, ophthalmic insertswere specifically given in BP.

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