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Syphilis is a systemic disease caused by the spirochete Treponema pallidum. The disease has been classically divided into a series of stages based on clinical findings [1]. The first stage of syphilis, known as primary syphilis, is marked by the presence of a chancre (a painless indurated ulcer with sharp borders that usually resolves within 3 to 6 weeks) at the site of inoculation (usually the genitals).