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Next-generation sequencing (NGS) allows to effectively performing whole genome sequencing (WGS) that may lead to the introduction of new genome-based analyses into clinical practice . WGS is one of very few recent developments in medicine which are characterized by the attributes ‘better’, ‘faster’ and ‘cheaper’. With the most recent development of NGS technologies (i.e., Illumina HiSeqX-Ten), complete sequencing of the human genome is feasible within a day for less than US $ 1'000 (not including costs for curation). Several companies offer NGS solutions and compete for a market share.
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