alexa Estradiol Synthesis and Metabolism and Risk of Ovarian Cancer in Older Women Taking Prescribed or Plant-derived Estrogen Supplementation

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Estradiol Synthesis and Metabolism and Risk of Ovarian Cancer in Older Women Taking Prescribed or Plant-derived Estrogen Supplementation

All steroid hormones, of which estradiol is an example, are lipids that have cholesterol as their common precursory substrate. The synthesis of sex steroid hormones from cholesterol involves a series of sequential steps that result in the cleavage of side-chains, reorganization of olefinic bonds, and the addition of hydroxyl groups.

 
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