alexa Dronedarone: Who, When, Why And How Should It Be Prescribed And Monitored?

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Dronedarone: Who, When, Why And How Should It Be Prescribed And Monitored?

Dronedarone is defined as "an oral anti-arrhythmic drug (ADD), indicated for clinically stable patients with a history of non-permanent atrial fibrillation (AF), for preventing recurrence of AF, or reducing ventricular rate (VR)." It is “a non-iodinated benzofuran derivative of amiodarone”. It potentially blocks multiple ion currents, “including the rapidly activating delayed-rectifier potassium current, the slowly activating delayed-rectifier potassium current, the inward rectifier potassium current, the acetylcholine activated potassium current, peak sodium current, and L-type calcium current, and exhibits antiadrenergic effects [2].” It is also used for the maintenance of sinus rhythm and ventricular response control during atrial fibrillation episodes.

Citation: Alqahtani MT (2015) Dronedarone: Who, When, Why And How Should It Be Prescribed And Monitored?. J Pharmacovigilance 3:169.

 

 
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