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Fish is an essential component of daily diet of many people in Bangladesh. Our country is the land of rivers and floodplains which has a high potential of aquatic resources where fish plays a very important role. Traditionally, people of Bangladesh like to eat fresh fishes where chilled and dried fishes are also marketed in large quantities around 70% fresh fish, 25% dried and the other forms of locally processed fish include fermented and frozen products [1]. Like human and other animals, fish suffers from diseases and infected with parasites. Fish defenses against disease are specific and non-specific, where nonspecific defenses include skin and scales, as well as the mucus layer secreted by the epidermis that traps microorganisms and inhibits their growth. If pathogens breach these defenses, fish can develop inflammatory responses that increase the flow of blood to infected areas and deliver white blood cells that attempt to destroy the pathogens.