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Lassa Fever (LF) continues to be major public health concern in Nigeria, Liberia, Sierra Leone and Guinea, as it is among the largest burden of viral hemorrhagic fevers in West Africa after Yellow Fever and the 2014 Ebola Viral Disease outbreak. The populations at risk in Sierra Leone, Guinea, and Nigeria may be as high as 59 million, with an annual incidence of illness of 3 million, and mortality as high as 67,000. LASV has been associated with nosocomial outbreaks with high mortality, and LF cases have been “exported” into the United States of America and Europe by viremic travelers from endemic areas. The increasing LF incidence outside endemic regions, due in part to the increased frequency of international travel, necessitates that health care providers, who are at the highest risk for infection because of their frequent contact with infected patients and their blood or bodily fluids, have comprehensive information on LASV infection.
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