Tuberculosis meningitis (TM) represents nearly 2% of all the cases. In HIV-infected patients the rate increases roughly 10%. This form of presentation is particularly important because of the significant high rate of mortality and disability (about half of the people affected) . Reason why it is considers the most severe mode of tuberculosis in children, adult and particularly in HIV diseased patient´s. The vaccination (Bacillus Calmette-Guérin) offers protection against disseminated forms of childhood tuberculosis, especially meningitis, but is not available worldwide.