alexa Simulation of a Microfluidic Gradient Generator using Lattice Boltzmann Methods

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Simulation of a Microfluidic Gradient Generator using Lattice Boltzmann Methods

Microfluidics provides a powerful and versatile technology to accurately control spatial and temporal conditions for cell culturing and can therefore be used to study cellular responses to gradients. Here we use Lattice Boltzmann methods (LBM) to solve both the Navier-Stokes equation (NSE) for the fluid and the coupled convection-diffusion equation (CDE) for the compounds that form the diffusion-based gradient. The design of a microfluidic chamber for diffusion-based gradients must avoid flow through the cell chamber.

Citations: Tanaka S, Iber D (2013) Simulation of a Microfluidic Gradient Generator using Lattice Boltzmann Methods. Curr Synthetic Sys Biol 1: 102.

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