Novel Avian Flu A

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Novel Avian Flu A

Avian influenza A (H7 N9 ) virus, the latest avian influenza virus strain was once considered a relatively rare cause of infection and low pathogenic . This virus is similar to its closer cousins, H7 N2 , H7 N3 and H7 N7 and its more distant cousin H5 N1 viruses which are all influenza A viruses and usually infect birds [1]. The virus has 8 single stranded ribonucleic acid (RNA) segments with 11 proteins (cap recognition RNA polymerase (basic) (PB2), endonuclease, elongation RNA polymerase subunit (basic) (PB1: Pol & PB1-F2), RNA polymerase subunit (acidic) (PA), hemagglutinin (HA), Nucleoprotein RNA binding RNA synthesis (NP), neuraminidase (NA), matrix protein 1 (M1), ion channel (M2), NS1 and NEP encoding . It currently remains unknown zoonotic outbreak if the H7 N9 virus is being transmitted from wild bird reservoir to poultry with sporadically transmission to humans in multiple unknown locations, most probable the live-bird markets (72% of cases reported some recent contacts with live-poultry and live-bird markets ), probably facilitated by the fact that people in China still buy poultry for domestic consumption underwent through both intra-provincial and inter-provincial trading [4] and supported by a reduction in the number of new human cases that associated with the closure of live-poultry markets in Shanghai or if the virus has spread to the affected provinces through poultry-topoultry transmission like scenario in eastern China whereas the novel virus causes mild or no disease in birds and poultry and lower pathogenic compared with avian influenza A (H5 N1 ) viruses .

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