Artesunate is a white crystalline powder odorless and almost tasteless. Artesunate has an excellent anti-malarial activity on the asexual forms of malaria parasites with high, quick efficiency to bring about rapid control of an acute attack. It has advantages of no cross resistance to Chloroquine. The concentration in plasma decreases rapidly after administered intravenously. The plasma half- life time is about 30 minutes. It distributes widely throughout the body and with high concentration in intestines, liver and kidneys. Only a small quantity excretes in urine and stools. It is mainly eliminated by metabolic bio-transformation. Artesunate is developed for killing the erythrocytic stage of plasmodium asexual form. It is effective to malaria caused by chloroquine resistant strain of plasmodium falciparum. It can quickly and reliably control the acute attack of malaria. It is suitable to salvage the patients with pernicious malaria and treat P. falciparum malaria and P. vivax malaria. Artesunate Injection is indicated for the treatment of serious malaria infections and the patients with cerebral malaria.
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