alexa Zoledronic Acid Induced Osteonecrosis of the Jaw

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Zoledronic Acid Induced Osteonecrosis of the Jaw

A 68 years male, case of IgG type multiple myeloma ΙΙΙA was on Bortezomib and Dexamethasone. Patient was simultaneously receiving Zoledronic acid 4 mg in 100 ml normal saline over 15 minutes infusion once every 28 days. After 16 injections of Zoledronic acid, he had pain in left lower jaw. On examination he had bone loss in the lingual aspect of left mandibular alveolus near 1st molar tooth area. There was no discharge or swelling. Orthopantomograph (OPG) showed a large osteolytic lesion at the site of clinical inflammation. Histopathology of scrapings ruled out plasmacytoma. Our final diagnosis was Zoledronic acid related osteonecrosis of the jaw. Zoledronate was stopped.

  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger