alexa Extending the Therapeutic Scope for the Treatment of Neuropathic Pain with Topical Analgesics

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Extending the Therapeutic Scope for the Treatment of Neuropathic Pain with Topical Analgesics

Neuropathic pain is defined as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system” . Peripheral nerve damage causes the release of pro-inflammatory mediators (including interleukin-1β, tumor necrosis factor-α, bradykinin, substance P, calcitonin gene-related peptide, nerve growth factor, and prostaglandins) contributing to the ‘inflammatory soup’ The inflammatory response has adaptive functions enabling nerve repair .

 
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