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Blood Disorders & Transfusion Journal is a peer reviewed and open access journal aimed to publish most interesting and complete reliable source of information on current development and advanced research findings in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide.
Journal of Blood Disorders & Transfusion is an academic journal that focuses on all aspects of molecular genetics, pathophysiology and epidemiology as well as prevention, diagnosis, and management of blood disorders with current state of research in the field of transfusion medicine, hematology, hemato-oncology, pediatric hematology, laboratory hematology, Neuropathy, Blood Donors, Thalassemia, Bone Marrow Transplantation, Anti-HBc, Haemodilution, hemodialysis, Blood Stem Cell, blood disorders, Rh factor, blood cancer, Platelet disorders, Hemolytic Anemia etc.
The journal is using Editorial Manager System for quality in review process. This is an online manuscript submission, review and tracking systems used by most of the best open access journals. Review process is performed by the editorial board members of the Journal of Blood Disorders & Transfusion or outside experts; at least two independent reviewer’s approval followed by the editor approval is required for acceptance of any citable manuscript.
Blood group is a classification of blood cells based on the presence or absence of inherited antigenic substances on the surface of red blood cells (RBCs). Blood group is also called as blood type. Genetic makeover is bought by respective parents determining which antigen is present on the red blood cells. This helps to find out the father of a child.
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Haemostasis is a process of formation of clot bleeding to stop bleeding that is the first stage of wound healing. Hemostasis occurs when blood cells is present outside of the body or blood vessels. Hemostasis has three major steps: 1) vasoconstriction, 2) temporary blockage of a break by a platelet plug, and 3) blood coagulation, or formation of a fibrin clot.
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Sickle cell disease is caused by a genetic abnormality in the gene for hemoglobin, which results in the production of sickle hemoglobin. When oxygen is released from sickle hemoglobin, it sticks together and forms long rods, which damage and change the shape of the red blood cell. The sickle red blood cells cause the symptoms of sickle cell disease.The sickle-shaped red blood cells break apart easily, causing anemia.
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Lymphocytes are an important part of the immune system. A count significantly higher than 3,000 lymphocytes in a microliter is generally considered to be lymphocytosis in adults. In children, the threshold for lymphocytosis varies with age, but may be as high as 7,000 to 9,000 lymphocytes per microliter. Lymphocytosis or a high lymphocyte count, is an increase in white blood cells called lymphocytes.
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Auto immune disorder is a disorder occurs when antibodies attack the same tissues of the body believing it as antigens. Symptoms depend on the disorder occurred and at the site of the body affected. Immunosuppresants are used as treatment of auto immune disorder.
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Autoimmune disorder journal, Immunotherapy: Open Access, Immunome Research
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SLE is also known as discoid lupus or disseminated lupus erythematous. An autoimmune disease occurs when the immune system attacks its own body. Symptoms can vary and can change over time. SLE most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system.
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Lupus journals, Lupus: Open Access
Red blood cell, also called erythrocyte, cellular component of blood cell which in the circulation of vertebrates gives its characteristic colour and carry oxygen from the lungs to the tissues.
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White blood cells are an important part of immune system and to defense against infectious organisms and foreign substances. White blood cells are also called white corpuscle or leukocytes. White blood cells defend the body adequately.
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Antiphospholipid syndrome (APS) is a disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss. Characteristic laboratory abnormalities in APS include persistently elevated levels of antibodies directed against membrane anionic phospholipids (ie, anticardiolipin [aCL] antibody, antiphosphatidylserine) or their associated plasma proteins, predominantly beta-2 glycoprotein I (apolipoprotein H); or evidence of a circulating anticoagulant.
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Leukopenia is a reduction in the circulating WBC count to < 4000/μL. It is usually characterized by a reduced number of circulating neutrophils, although a reduced number of lymphocytes, monocytes, eosinophils, or basophils may also contribute which leads to great decrease in immune function.
Leukopenia may be caused by various diseases and drugs. Antidepressant and smoking addiction treatment medication called Bupropion and antibiotic Minocycline and penicillin may also cause leukopenia. Treatment of leukopenia depends on the cause of the condition. Some medical treatments can temporarily deplete the body of white blood cells. Chemotherapy, radiation therapy, antibiotics or diuretics can kill off white blood cells as the medications target fast growing tissues throughout the body.
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Blood cancers occur due to abnormal production and function of your blood cells. Most of these cancers in bone marrow where blood cell is produced. Stem cells in bone marrow mature and develop into three types of blood cells: red blood cells, white blood cells, or platelets. In most blood cancers, the normal blood cell development process is interrupted by uncontrolled growth of an abnormal type of blood cell. These abnormal blood cells, or cancerous cells, prevent blood cell from performing many of its functions, like fighting off infections or preventing serious bleeding.
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Autoimmune hemolytic anemia is a group of disorders characterized by a malfunction of the immune system that produces autoantibodies, which attack red blood cells as if they were substances foreign to the body. Autoimmune hemolytic anemia is an uncommon group of disorders that can occur at any age. These disorders affect women more often than men. Autoimmune hemolytic anemia can also be caused by or occur with another disorder, such as systemic lupus erythematosus (lupus), and rarely it follows the use of certain drugs, such as penicillin.
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Increase in the number of eosinophils in the blood cell is called Eosinophilia and occurs in response to some allergens, drugs, and parasites, and in some types of leukaemia. Peripheral blood cell eosinophil count is >500/ μl. Eosinophilia can be idiopathic, the disease may be controlled with corticosteroids.
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Lymphocytosis is an increase in the number or proportion of lymphocytes in the blood cells i.e. Lymphocyte count is more than 5000/ml. Causes of Lymphocytosis include viral infection, Lymphoproliferative disorder, Toxoplasmosis, etc. Lymphocytosisis commonly short lived.
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Juvenile myelomonocytic leukemia is found in children as an aggressive pediatric myelodysplastic syndrome (MDS)/myeloproliferative disorder (MPD) symptomized by malignant transformation in the hematopoietic stem cell compartment with proliferation of differentiated progeny . JMML constitutes approximately 30% of childhood cases of myelodysplastic syndrome and 2% of leukemia. JMML and CMML have a high frequency of mutations affecting the RAS signaling pathway and show hypersensitivity to stimulation with GM-CSF, which causes STAT5 hyperphosphorylation.
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Neutropenia is a decrease in circulating neutrophils in the nonmarginal pool, which constitutes 4-5% of total body neutrophil stores. Most of the neutrophils are contained in the bone marrow, either as mitotically active (one third) or postmitotic mature cells (two thirds). Tuberculosisis one type of infection that may cause neutropenia.
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Hemolytic disease of the newborn (HDN) is blood disorder in a fetus or newborn infant and major cause is fetal loss and death among newborn babies. Hemolytic disease of the newborn (HDN) is also called as erythroblastosis fetalis. More occurs during a mother's second or subsequent pregnancy.
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Hemolytic anemia occurs when the bone marrow is unable to replace the red blood cells that are being destroyed. Hemolytic anemia is a type of anemia. Hemolytic anemia is caused by high rates of red blood cell destruction i.e. erythrocytic loss which results in improper bone marrow activity. Initial stages of haemolysis are asymptomatic but in final stage s of haemolysis causes angina and cardio pulmonary diseases sometimes leads to death.
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Abnormality in Plasma cell results in plasma cell disorders. Plasma cell disorders are uncommon. Single plasma cell multiplies excessively which results in increasing number of abnormal plasma cells results damages of various tissues and organs.
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Neutrophilic leukocytosis is caused due increase in number of neutrophils (a type of white blood cell) in the blood. Neutrophils help the body fight infections and heal injuries.
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*2016 Journal Impact Factor was established by dividing the number of articles published in 2014 and 2015 with the number of times they are cited in 2016 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2014 and 2015, and 'Y' is the number of times these articles were cited in indexed journals during 2016 then, impact factor = Y/X