alexa Acute lymphocytic leukemia | Brazil | PDF | PPT| Case Reports | Symptoms | Treatment

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Acute Lymphocytic Leukemia

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  • Acute lymphocytic leukemia

     Acute lymphoblastic leukemia, also known as acute lymphocytic leukemia or acute lymphoid leukemia (ALL), is an acute form ofleukemia, or cancer of the white blood cells, characterized by the overproduction and accumulation of cancerous, immature white blood cells, known as lymphoblasts.

    Typical Symptoms 

    • Generalized weakness and fatigue, Anemia, Dizziness, Weight loss and/or loss of appetite, Excessive and unexplained bruising, Bone pain, joint pain (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity), Enlarged lymph nodes, liver and/or spleen, Petechiae, which are tiny red spots or lines in the skin due to low platelet levels.

  • Acute lymphocytic leukemia

     Treatment and Medication

    Chemotherapy, Remission induction, Consolidation, Maintenance therapy, Immunotherapy, Biological therapy, Radiation therapy.

  • Acute lymphocytic leukemia

     Statistics

    Data were examined from 16 PBCRs in Brazilian cities located in five geographical regions during the period from 1997 to 2004. Incidence rates were analyzed according to gender, age, and type of leukemia. The Wilcoxon test was performed to evaluate for gender-age based difference between by leukemia type.The median age-adjusted incidence rate (AAIR) of leukemia in children aged 0-14 years old was 53.3 per million. A different AAIR was found regarding ALL and myeloproliferative disorders (MPD) that ranged from 24.8 to 76.84 per 1,000,000 children. Manaus, although located in a poor area of Brazil, exhibited the highest AAIR (56.6 per million) of ALL. Goiania had the highest AAIR (24.5 per million) of MPD. The median age-specific incidence rate (ASIR) for the 16 Brazilian PBCRs demonstrated a marked peak in incidence of ALL at age 3 years old, in both genders.

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