Ampullary cancer is a malignant tumor that arises from the Ampulla of Vater, the last centimeter of the common bile duct as it passes through the duodenum, the first section of the intestine. The diagnostic tests used to for ampullary cancer are similar to those for pancreatic cancer; endoscopy or endoscopic retrograde cholangiopancreatography (ERCP) are frequently used to make the diagnosis.A tumor blocking the Ampulla of Vater will interfere with drainage of the pancreatic and biliary secretions into the intestine.
If your doctors determine that you have ampullary cancer, the standard approach is to remove the tumor from the ampulla of Vater with a procedure called pancreaticoduodenal resection, or Whipple procedure. This procedure involves the resection, or removal, of the tumor in the affected portion of the ampulla of Vater and the surrounding areas.
In the Far East, Korea demonstrated highly significant increasing mortality trends for both sexes [men (4.8–7.8), p<0.001; women (2.5–4), p<0.01), while women in Japan showed an increasing trend that was significant (p<0.05). In France, a trend towards increasing mortality was observed among women (p<0.001). An upward mortality trend in women achieving significance was also seen in Malta, Bulgaria, Greece, and Germany (p<0.05). A decline in mortality was seen in both sexes only in Canada [men (7.5–6.4), women (5.9–5); p<0.01], while for men there was a downward trend noticeable in Ireland, Switzerland, Austria, the UK, and Poland [p<0.05].